… in immune cells in the tumour microenvironment, leading to loss of … In a cervical cancer
cell line, celecoxib increased … in normal and cancer cells; although these biomarkers and cell …

… that celecoxib is effective in the advanced stages of cancer. … survival of patients in prostate,
cervical, skin, and bladder cancer. … Phase I/II, III/IV clinical trials in collaboration with NCI and …

… -label single arm phase I-II trial which is assessing veliparib (PO … It has been reported that
the tumor microenvironment … is being studied in a prospective phase III trial. There is a strong …

… (70%-80%) of NPC patients present with cervical lymph node … clinical stages (III/IV) compared
to early localized stages (I/II) (… focused on molecular biomarkers for cancers, including NPC…

… cells in the tumor microenvironment (TME), promoting cancer … synthase 1 (PTGS1), and
cyclooxygenase-2 (COX-2), officially … For example, celecoxib was shown to inhibit HCC cell …

… , the carcinogenic tissue microenvironment in the remnant … New HCC biomarkers and imaging
modalities may improve … example skin, cervix, and gastrointestinal tract cancers) that have …

… carcinogenesis, as well as the involvement of cyclooxygenase-2 (… COX-2 Tumor
microenvironment and inflammation Cancer … that treating cervical cancer patients with celecoxib …

… the tumour microenvironment (TME) supports cancer cell … ) in a phase I/II trial involving
patients with metastatic melanoma (… treatment with the NSAID COX2 inhibitor celecoxib. PGE 2 –…

… and its metabolites as biomarkers for screening of gastric cancer. Deng et al. indicated
that … in tumor cells. Thereafter, high level of kynurenine in the tumor microenvironment is …

… the development of cancer. The microenvironment surrounding the tumor is greatly influenced
… 1-alpha through the activation of cyclooxygenase-2 and the NF-кB inflammatory signaling …